Been following this from the start and I seem to think this is the Erie 28th Street yard, looking east from the vicinity of the West Side Highway. The building in the right  background looks like the Erie freight-house, with the stepped brick facade. This yard was on the southwest side of Manhattan, served by an Erie float bridge. It was one city block wide and 1.5-2 city blocks long. Eleventh thru 13th Avenues (run north south in Manhattan) There were a number of yards in the vicinity, with the LV and B&O just south of the Erie. All car float served. The NYC had a direct connection further  North in Manhattan, so no float bridge needed there. Busy scene, but long closed.